- Chemistry (Organic)
Nature of the Research
- Wet lab/bench research
- Field research
- Informatics/computational research
- Basic research
- Systems: Living systems are interconnected and interacting.
- Applying the process of science
- Using quantitative reasoning
- Tapping into the interdisciplinary nature of science
- Communicating and collaborating
- What is the relationship between host plants (e.g. location or species) and the resident endophytes or the products they produce?
- Do endophytes produce natural products of interest in a particular assay (antibiotics, products that induce growth of plants, etc.)?
- What is the phylogenetic relationship between a student-isolated endophyte and other microbes?
- Identify a biological question and frame it as a scientifically testable statement.
- Identify and execute methods to answer the question.
- Analyze and interpret the results obtained.
- Communicate the results orally and in written form.
This project uses endophyte diversity as a platform for investigating ecological questions, microbial characterization, and isolation and characterization of natural products produced by these microbes. A version of this program has been implemented with high school students, undergraduates and medical students. The duration of the module has ranged from a few day workshop to a semester-long course followed by a summer of full time research. The course synthesizes lecture, field-work, and laboratory experiences and emphasizes the multidisciplinary nature of science. Projects can be tailored to meet the faculty expertise and financial resources at the implementing institution.
Bascom-Slack, C.A., Arnold, A.E., Strobel, S.A. (2012) Student-Directed Discovery of the Plant Microbiome and Its Products Science 338:485-486
Strobel, S.A and Strobel, G.A. (2007) Plant Endophytes as a Platform for Discovery-Based Undergraduate Science Education Nat. Chem. Biol. 3:356-359
Information available in the supplementary materials section of Science 338:485-486 (2012)